Study of effect of devitalization technique at mini-pigs
(summary
of experimental results from 1991-2000)
Translation from the Czech
original by Martin Tlusty
Table 1.
|
DEVITALIZED TISSUE or ORGAN |
NUMBER OF ANIMALS (pcs) |
MORTALITY (pcs) |
CAUSATION |
SUCCESS RATE (%) |
NOTE | |
intestines+
digestive tract |
jejunum |
14 |
0 |
|
100 |
animals without tumors |
|
ileum |
14 |
1 |
pneumonia |
93 |
animals without tumors | |
|
intestine |
7 |
0 |
|
100 |
animals without tumors | |
|
coecum |
10 |
1 |
ileotic condition (heavy ascariasis) |
90 |
animals without tumors | |
|
ileum + coecum |
7 |
0 |
|
100 |
animals without tumors | |
ileum +coecum +intestine |
4 |
0 |
|
100 |
animals without tumors | |
|
sigmoideum |
8 |
0 |
|
100 |
animals without tumors | |
|
rectum |
6 |
0 |
|
100 |
animals without tumors | |
|
stomach |
25 |
2 |
peritonitis (untightness of anastomosis) |
92 |
animals without tumors | |
|
phlegmon of tongue | ||||||
|
| ||||||
|
½ stomach + spleen + ¾ pancreas |
1 |
0 |
|
only
1 animal |
animal without tumors | |
|
spleen |
1 |
0 |
|
only
1 animal |
animal without tumors | |
|
| ||||||
|
kidney |
w |
18 |
0 |
|
100 |
animals without tumors |
|
segmental |
29 |
0 |
|
100 |
animals without tumors | |
|
| ||||||
|
liver |
1 |
0 |
|
only
1 animal |
animal without tumors | |
|
lungs |
5 |
0 |
|
100 |
animals without tumors | |
|
| ||||||
|
melanoma |
skin tumor |
59 |
6 |
dehydration |
90 |
only 3 deaths caused by progression of
melanoma
! |
|
histaminic shock | ||||||
|
pneumonia |
survival up to 10 months (termination
of the trial test) or up to 6 years (in breeding) without relapse of
tumor ! | |||||
|
progression of melanoma | ||||||
|
progression of melanoma | ||||||
|
progression of melanoma | ||||||
|
spleen with metastasis |
13 |
0 |
|
100 | ||
|
node with metastasis |
7 |
0 |
|
100 | ||
Study of effect of devitalization technique at other animal species
(summary of experimental results from 1991-2000)
Table 2.
|
SPECIES |
DEVITALIZED
PART, ORGAN or TUMOR |
NUMBER OF ANIMALS
(pcs) |
MORTALITY (pcs) |
CAUSATION |
SUCCESS RATE (%) |
NOTE | |
|
laboratory rat |
small intestine (ileum) |
10 |
0 |
|
100 |
animals without tumors | |
|
kidney |
whol |
20 |
0 |
|
100 |
animals without tumors | |
|
segmental |
117 |
3 |
uremia |
97 |
animals without tumors | ||
|
liver |
16 |
0 |
|
100 |
animals without tumors | ||
|
| |||||||
|
rabbit |
small intestine (jejunum) |
2 |
0 |
|
only 2 animals |
animals without tumors | |
|
kidney (whole) |
2 |
0 |
|
only 2 animals |
animals without tumors | ||
|
| |||||||
|
cat |
fibrosarcoma |
1 |
0 |
|
only 1 animal |
| |
|
| |||||||
|
dog various races |
tumor of mammary gland |
51 |
17 |
relapse or progression of
the tumor |
67 |
| |
|
lymphom |
1 |
0 |
|
only 1 animal |
| ||
|
melanoma |
3 |
0 |
|
100 |
| ||
|
sarcoma |
1 |
0 |
|
only 1 animal |
| ||
|
n |
1 |
1 |
hypoglycemia |
only 1 animal |
| ||
|
carcinoma (stomach)
|
2 |
1 |
complication
during operati |
only 2 animals |
| ||
|
adenocarcinoma |
1 |
0 |
|
only 1 animal |
| ||
|
osteosarcoma |
1 |
1 |
progression of tumor |
only 1 animal |
| ||
|
lymphosarcom |
1 |
1 |
complication
during operati |
only 1 animal |
| ||
Study of effect of devitalization technique at dogs
(summary of experimental results from 1991-2000)
Table 3.
Length of survival versus age of the animal
|
LENGTH OF
SURVIVAL |
AGE CATHEGORY | |||||
|
5 – 8 years (n = 11) |
9 – 11 years (n = 14) |
12 years and more (n = 5) | ||||
|
number of animals (pcs) |
% |
number of animals (pcs) |
% |
number of animals (pcs) |
% | |
|
2 months |
0 |
0 |
1 |
7,1 |
0 |
0 |
|
2 – 5 months |
5 |
45,5 |
4 |
28,6 |
0 |
0 |
|
5 – 12 months |
5 |
45,5 |
5 |
35,7 |
4 |
80 |
|
12 months |
1 |
9,1 |
4 |
28,6 |
1 |
20 |