Study of effect of devitalization technique at mini-pigs

 (summary of experimental results from 1991-2000)

Translation from the Czech original by Martin Tlusty

Table 1.

DEVITALIZED TISSUE or ORGAN

NUMBER OF ANIMALS (pcs)

MORTALITY (pcs)

CAUSATION

SUCCESS RATE (%)

NOTE

    intestines

       +

digestive tract

               jejunum

    14

0

 

100

animals without tumors

ileum

14

1

pneumonia

  93

animals without tumors

intestine

  7

0

 

100

animals without tumors

coecum

10

1

ileotic condition (heavy ascariasis)

  90

animals without tumors

ileum + coecum

  7

0

 

100

animals without tumors

   ileum +coecum +intestine

  4

0

 

100

animals without tumors

sigmoideum

  8

0

 

100

animals without tumors

rectum

  6

0

 

100

animals without tumors

stomach

25

2

peritonitis (untightness of anastomosis)

  92

animals without tumors

phlegmon of tongue

 

½ stomach + spleen + ¾ pancreas

  1

0

 

only 1 animal

animal without tumors

spleen

  1

0

 

only 1 animal

animal without tumors

 

kidney

whole

18

0

 

100

animals without tumors

segmental

29

0

 

100

animals without tumors

 

liver

  1

0

 

only 1 animal

animal without tumors

lungs

  5

0

 

100

animals without tumors

 

melanoma

skin tumor

59

6

dehydration

  90

only 3 deaths caused by progression of melanoma !

histaminic shock

pneumonia

survival up to 10 months (termination of the trial test) or up to 6 years (in breeding) without relapse of  tumor !

progression of melanoma

progression of melanoma

progression of melanoma

spleen with metastasis

13

0

 

100

node with metastasis

  7

0

 

100

 

Study of effect of devitalization technique at other animal species

 (summary of experimental results from 1991-2000)

Table 2.                           

SPECIES

DEVITALIZED PART, ORGAN or  TUMOR

NUMBER OF ANIMALS (pcs)

MORTALITY (pcs)

CAUSATION

SUCCESS RATE (%)

NOTE

laboratory rat

small intestine (ileum)

  10

0

 

100

animals without tumors

kidney

whole

  20

0

 

100

animals without tumors

segmental

117

3

uremia

  97

animals without tumors

liver

  16

0

 

100

animals without tumors

 

rabbit

small intestine (jejunum)

    2

0

 

only 2 animals

animals without tumors

kidney (whole)

    2

0

 

only 2 animals

animals without tumors

 

cat

fibrosarcoma

    1

0

 

only 1 animal

 

 

dog

 

various races

tumor of mammary gland

51

17

relapse or progression of the tumor

 67

 

lymphoma

  1

  0

 

only 1 animal

 

melanoma

  3

  0

 

100

 

sarcoma

  1

  0

 

only 1 animal

 

node

  1

  1

hypoglycemia

only 1 animal

 

carcinoma (stomach)

  2

  1

complication during  operation

only 2 animals

 

adenocarcinoma

  1

  0

 

only 1 animal

 

osteosarcoma

  1

  1

progression of tumor

only 1 animal

 

lymphosarcoma

  1

  1

complication during  operation

only 1 animal

 

 

 

Study of effect of devitalization technique at dogs

 (summary of experimental results from 1991-2000)

Table 3.                           

Length of survival versus age of the animal

LENGTH OF SURVIVAL

AGE CATHEGORY

5 – 8 years (n = 11)

9 – 11 years (n = 14)

12 years and more (n = 5)

number of animals (pcs)

%

number of animals (pcs)

%

number of animals (pcs)

%

2 months

0

0

1

7,1

0

0

2 – 5 months

5

45,5

4

28,6

0

0

5 – 12 months

5

45,5

5

35,7

4

80

12 months and more

1

9,1

4

28,6

1

20